Antaeus - TITAN
-Highly potent anabolic.
-Non-hormonal, thus no need for PCT or liver/cycle support.
-Heart-healthy, may assist with lipid and cholesterol support.
-Naturally extracted from the tomato plant.
-Complexed with shilajit for vastly enhanced solubility and bioavailability.
-Shilajit may assist with muscle growth and may provide testosterone support.
TITAN is Tomatidine --
simply the most potent natural anabolic available. [1-3] In a direct
comparison to ursolic acid, it was shown to be nearly 10-fold more
potent. It was also discovered to be nearly 5-fold more orally
bioavailable. It increases mTOR signalling in skeletal muscle, inhibits
the ATF4 pathway, and dramatically stimulates protein synthesis. Of
particular benefit to power athletes and bodybuilders is the fact that
it stimulates growth primarily in Type IIb and Type IIx muscle fibers --
the power fibers with the most potential for growth.
Although tomatidine is,
as previously mentioned, more orally bioavailable than ursolic acid, it
still displays extremely poor aqueous solubility -- estimated at
0.000189 mg/mL  -- which places hard limits on its oral
bioavailability. To sidestep this issue, we've complexed tomatidine
with shilajit. Shilajit, which has been used as a tonic and
rejuvenating agent for centuries, is a fully water-soluble mixture of
fulvic acids, humic acids, and minerals. Much like cyclodextrins, it is
capable of binding small molecules like tomatidine and forming
amorphous, water-soluble complexes. [5-7] Our tomatidine-shilajit
complex is orders of magnitude more water-soluble than pure tomatidine, a
fact which boosts its bioavailability to heights otherwise out of
The fact that shilajit
has itself been shown to assist with muscle growth, and boost
testosterone levels in healthy young men, is just a bonus. [8-9]
As is the fact that tomatidine is proven heart-healthy, and may be able to assist with cholesterol and lipid support. [10-11]
...The important thing is that TITAN is the most potent natural anabolic available.
Accept no substitute.
TITAN has been rigorously tested, results are publicly available, and a
patent is pending. TITAN uses top-quality tomatidine (standardized to
over 95% purity) and shilajit (standardized to 50%+ fulvic acids).
[1. Dyle MC, Ebert SM,
Cook DP, et al. Systems-based discovery of tomatidine as a natural small
molecule inhibitor of skeletal muscle atrophy. J Biol Chem.
2. Ebert SM, Dyle MC, Bullard SA, et al. Identification
and Small Molecule Inhibition of an Activating Transcription Factor 4
(ATF4)-dependent Pathway to Age-related Skeletal Muscle Weakness and
Atrophy. J Biol Chem. 2015;290(42):25497-511.
3. Adams CM, Ebert SM, Dyle MC. Use of mRNA expression
signatures to discover small molecule inhibitors of skeletal muscle
atrophy. Curr Opin Clin Nutr Metab Care. 2015;18(3):263-8.
4. Available at: http://www.hmdb.ca/metabolites/HMDB34731. Accessed November 9, 2016.
5. Agarwal SP, Anwer MK, Aqil M. Complexation of
furosemide with fulvic acid extracted from shilajit: a novel approach.
Drug Dev Ind Pharm. 2008;34(5):506-11.
6. Mirza MA, Ahmad N, Agarwal SP, Mahmood D, Khalid
anwer M, Iqbal Z. Comparative evaluation of humic substances in oral
drug delivery. Results Pharma Sci. 2011;1(1):16-26.
7. Mirza MA, Agarwal SP, Rahman MA, et al. Role of humic
acid on oral drug delivery of an antiepileptic drug. Drug Dev Ind
8. Das A, Datta S, Rhea B, et al. The Human Skeletal
Muscle Transcriptome in Response to Oral Shilajit Supplementation. J Med
9. Pandit S, Biswas S, Jana U, De RK, Mukhopadhyay SC,
Biswas TK. Clinical evaluation of purified Shilajit on testosterone
levels in healthy volunteers. Andrologia. 2016;48(5):570-5.
10. Fujiwara Y, Kiyota N, Tsurushima K, et al.
Tomatidine, a tomato sapogenol, ameliorates hyperlipidemia and
atherosclerosis in apoE-deficient mice by inhibiting
acyl-CoA:cholesterol acyl-transferase (ACAT). J Agric Food Chem.
11. Friedman M. Anticarcinogenic, cardioprotective, and
other health benefits of tomato compounds lycopene, α-tomatine, and
tomatidine in pure form and in fresh and processed tomatoes. J Agric
Food Chem. 2013;61(40):9534-50.
*These statements have not been
evaluated by the Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.